Effect of Salix alba leave extract on growth performance, antioxidant level and immune status of broiler chickens reared at high altitude cold desert

Extremes of climate and hypobaric hypoxia cause poor growth performance in broiler chickens at high altitude the present study investigates effect aqueous extract Salix alba leaves on performance, antioxidant level immune status reared cold desert (3500 m). High liquid chromatography (HPLC) analysis revealed presence salicin caffeic acid. In vitro efficacy evaluation that had a significant cytoprotective lymphocytes. For in-vivo study, total 105 one d old RIR cross-bred were randomly assigned to seven groups: 1) Control fed basal diet 2) Six treatments + S. @100, 150, 200, 300, 400, 800 mg kg−1 body weight chicken, respectively. Chickens 300 group greater (p < 0.05) improved feed conversion ratio (FCR) compared other treatments. Furthermore, capacity (TAC), free radical scavenging activity, interleukin-2, lower malondialdehyde (MDA), interleukin-1, interleukin-6 concentration as control group. Net profit was also increased all with due less mortality chickens. These findings indicated inclusion dose exhibited beneficial through immunomodulation up-regulation antioxidants, therefore, it has potential be used phytogenic additive for improving altitude.